Aspirin Side Effects Dosage And Low
Aspirin is one of the oldest medicines still in common use. It belongs to a class of medicines called salicylates and works by suppressing the production of certain substances in the body that cause pain, fever and inflammation.
Aspirin also affects platelets cells in the blood that are involved in clotting. Taking aspirin reduces the ability of platelets to stick together and form clots, making it useful in the treatment and sometimes prevention of conditions where blood clots form in arteries, such as heart attack and stroke.
Low-dose aspirin may be recommended on a daily basis for people who have already had a heart attack or stroke to prevent them from having another.
Side Effects Of Aspirin
The majority of people dont experience any side effects when taking aspirin however, some people will suffer side effects.
The main side effects of aspirin happen when it irritates the stomach, causing heartburn, nausea or vomiting.
Because aspirin thins your blood, making it harder to clot, taking aspirin can increase your risk of bleeding, including bleeding from the gastrointestinal tract. Bleeding from the stomach or gut is one of the most serious side effects of aspirin. For this reason, people with stomach or duodenal ulcers are usually advised not to take aspirin.
If you experience black tarry stools, or vomit blood or what looks like coffee grounds, contact your doctor immediately.
Aspirin can cause an allergic reaction in some people, resulting in skin rash, hives, wheezing and difficulty breathing. The reaction usually happens within an hour of taking the aspirin. You should get immediate medical help if this happens to you or someone else.
In high doses, aspirin may cause ringing in the ears or deafness.
Experts No Longer Recommend Aspirin Use To Prevent Heart Attack Stroke For Most Patients
Proposed new guidelines recommended against low-dose aspirin use for primary prevention of CVD in adults age 60 years or older, citing adverse effects.
Previously, a daily low-dose aspirin regimen was recommended by clinicians for heart health, particularly in the prevention of heart disease and stroke, considered the leading cause of mortality in the US.
But due to mounting evidence on the adverse effects of aspirin use, a new draft recommendation statement from the US Preventive Services Task Force reversed the 2016 recommendation statement on its use.
Now, the task force recommends clinicians should no longer prescribe low-dose aspirin use to most people at high risk of cardiovascular disease .
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Dosage For Acute Coronary Syndrome
The typical dosage of Plavix for acute coronary syndrome depends on whether you have:
- unstable angina
- non-ST-segment elevation myocardial infarction , a type of heart attack
- ST-segment elevation myocardial infarction , a type of heart attack
The typical dosage of Plavix is one 75-mg tablet taken by mouth once daily. It can be taken with or without food.
Your doctor may recommend that you start Plavix therapy by taking a loading dose. With a loading dose, the drug is given to you at a dosage higher than the typical dosage. A loading dose is used to increase the level of the drug in your body right away. The typical loading dosage of Plavix is 300 mg taken by mouth one time.
After taking your loading dose of Plavix, your doctor will recommend the dosage of Plavix that you should continue to take each day.
Missed Or Extra Doses
If you’re taking aspirin to reduce your risk of blood clots and you forget to take a dose, take that dose as soon as you remember. You should then continue to take your course of aspirin as normal.
If it’s almost time for the next dose, skip the missed dose and continue your regular schedule. Don’t take a double dose to make up for a missed one.
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When To Call The Doctor
- Ringing in the ears or problems hearing
- Dizziness or confusion
- Bruising, including small pinpoint or freckle-sized spots
- Bleeding problems like getting a cut to stop bleeding, nosebleeds, bleeding gums, blood in the stool or urine, black stools or vomit that looks like coffee grounds
- Unusual tiredness or weakness
- Skin rash or rash that itches
- Exposure to chicken pox or shingles
- Any side effects that continue or are very bothersome
Financial And Insurance Assistance
If you need financial support to pay for Plavix or if you need help understanding your insurance coverage, help is available.
Bristol-Myers Squibb, the manufacturer of Plavix, offers the BMS Access Support program, which may help to lower your cost of Plavix. To learn more information and to find out if youre eligible for support, call 800-861-0048 or visit the program website.
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Constipation Treatments To Try After Surgery
Purchase a laxative or stool softener before your surgery so that you have it available when you return home.
If over-the-counter laxatives dont work, your doctor may prescribe prescription drugs that draw water into your intestines to stimulate a bowel movement.
Linaclotide or lubiprostone are two such medications.
How Is Aspirin Poisoning Diagnosed
Most cases are diagnosed in pets that have the expected signs and a known or suspected exposure to aspirin. Blood work is necessary to evaluate the kidneys, liver, electrolytes, and blood cell counts. Radiographs of the chest can identify lung disorders secondary to aspirin poisoning. Tests to assess the pets blood clotting ability or acidity levels may also be performed.
Salicylate levels in the blood can be measured at a human hospital or specialized veterinary diagnostic laboratory. Testing for salicylate levels is not common in veterinary medicine. The results may not be returned quickly and finding a laboratory to run the testing for animals may be difficult. Since the results may be delayed, treatment is often started without testing if poisoning is suspected.
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Do I Need To Follow A Special Diet While Im Taking Plavix
No, you dont need to follow a special diet while youre taking Plavix. This drug should work safely and effectively for you regardless of your specific diet.
One exception to this is that your doctor may recommend that you avoid consuming grapefruit and grapefruit juice while youre taking Plavix. These products can interact with Plavix. For more information, see the Plavix interactions section above.
However, keep in mind that if youre taking Plavix, youve probably had a cardiovascular event, such as heart attack or stroke, or youre at a risk of having one. Eating a healthy, balanced diet will help to reduce your overall risk of heart disease and cardiovascular events.
Talk to your doctor about healthy foods you can eat to support your heart and blood vessels.
What Is The Most Important Information I Should Know About Aspirin
Using aspirin in a child or teenager with flu symptoms or chickenpox can cause a serious or fatal condition called Reye’s syndrome.
You should not use aspirin if you are allergic to it, or if you have:
- a recent history of stomach or intestinal bleeding
- a bleeding disorder such as hemophilia or
- if you have ever had an asthma attack or severe allergic reaction after taking aspirin or an NSAID .
Tell your doctor if you have ever had:
- asthma or seasonal allergies
- a bleeding or blood clotting disorder
- gout or
- heart disease, high blood pressure, or congestive heart failure.
Taking aspirin during late pregnancy may cause bleeding in the mother or the baby during delivery. Tell your doctor if you are pregnant or plan to become pregnant.
You should not breastfeed while using this medicine.
How Is Aspirin Poisoning Treated
There is no antidote for aspirin poisoning but early decontamination and treatment decrease the risk for serious harm. If aspirin ingestion occurred within a few hours of treatment, the veterinarian may induce vomiting. Once vomiting is controlled, activated charcoal may be administered. This can decrease absorption of aspirin by the gastrointestinal tract. Activated charcoal should only be administered by a veterinarian. Otherwise, aspiration into the lungs and life-threatening changes in blood sodium levels may occur. Antacids, anti-nausea medications and stomach protectants are commonly administered.
Depending upon the dose ingested, hospitalized care may be needed. Fluids may be administered under the skin or intravenously. Dogs developing more serious signs may require intensive therapy, because they have an increased risk for long term effects or death. Blood work to monitor the liver and kidney function as well as the red blood cell count may be performed. Pets that develop a low red blood cell count or difficulty breathing may require oxygen supplementation or a blood transfusion. Liver protectants, muscle relaxants, and medications to control seizures may be necessary.
My Doctor Said Im A Poor Metabolizer Of Plavix What Does That Mean
Plavix only works if your body is able to metabolize the drug. In order to metabolize Plavix, your body uses an enzyme called CYP2C19 thats found in your liver.
Every person has a different amount of this enzyme in their body. Some people have very little of it, while other people have a larger amount. The amount can vary because of a persons genetic makeup, or if theyve had liver problems in the past.
People with small amounts of CYP2C19 are considered poor metabolizers of Plavix, since their body cant break down the drug very well.
Your doctor may order a blood test to see if youre a poor metabolizer of Plavix before you start taking the drug. If youre a poor metabolizer, your doctor may recommend that you take a drug other than Plavix. Or they may give you a higher dosage of Plavix than is typically given.
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Side Effects Not Requiring Immediate Medical Attention
Some side effects of aspirin may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects.
Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:
Incidence not known
- stomach discomfort, upset, or pain
- trouble sleeping
- unusual drowsiness, dullness, tiredness, weakness, or feeling of sluggishness
Plavix And Other Medications
Below are lists of medications that can interact with Plavix. These lists do not contain all the drugs that may interact with Plavix.
Before taking Plavix, talk with your doctor and pharmacist. Tell them about all prescription, over-the-counter, and other drugs you take. Also tell them about any vitamins, herbs, and supplements you use. Sharing this information can help you avoid potential interactions.
If you have questions about drug interactions that may affect you, ask your doctor or pharmacist.
Plavix and certain proton pump inhibitors
Plavix can interact with certain other drugs that are metabolized by the same enzymes in your liver. For example, proton pump inhibitors are a class of drugs that are metabolized by the enzymes that break down Plavix. Taking these drugs with Plavix can make Plavix less effective for you. This may be dangerous to your health.
Examples of proton pump inhibitors that can decrease the effectiveness of Plavix include:
If youre taking one of the drugs listed above, talk with your doctor about whether its safe for you to use Plavix. They may recommend a different treatment so you can avoid this interaction.
Plavix and ibuprofen or other NSAIDs
Examples of NSAIDs that can increase your risk of bleeding include:
While youre using Plavix, talk with your doctor before you start taking any new medications, including pain relievers.
Plavix and warfarin or other blood thinners
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Drink Plenty Of Fluids
Water plays a large part in keeping your body healthy. It is essential for keeping fecal matter flowing through the intestines. Although most people have heard that you should drink six to eight glasses of water a day, you might not need to consume that much. Four to six cups of water per day are generally enough for healthy people, according to Harvard Health.
Some medications cause you to retain water, and some health conditions require you to limit your fluid intake. If you are taking medications that cause constipation, you should talk to your doctor about how much water you should be drinking.
Aspirin For Pain And Fever
Aspirin can be used for the occasional treatment of mild to moderate pain and fever. It can be used as a painkiller for conditions such as headaches and migraines, period pain, toothache, cold and flu symptoms and joint and muscle pains.
Aspirin should not be given to children younger than 16 years, especially if the child also has symptoms of influenza or chickenpox or has fever. This is because aspirin can cause a serious and sometimes fatal condition in children called Reyes syndrome .
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Why Do Vets Prescribe Aspirin For Dogs
Vets usually prescribe aspirin for dogs with osteoarthritis or musculoskeletal inflammation. The anti-inflammatory properties of aspirin help reduce the pain and inflammation associated with these conditions and can offer your dog relief from symptoms.
Veterinarians also use aspirin to treat a variety of other conditions. If you have a question about why your vet recommended administering aspirin, call the office. Thanks to some of the more serious side effects associated with the drug, aspirin is not a medication that owners should give their dogs without veterinary approval, so be sure to pay close attention to your veterinarians instructions.
Urgent Advice: Phone 999 Or Go To A& e If:
You are taking aspirin and have symptoms like:
- hives a raised, itchy rash
- tinnitus hearing sounds that come from inside your body
- breathing difficulties or an asthma attack
- an allergic reaction this can cause breathing problems, swelling of the mouth, lips or throat, and a sudden rash
- severe headaches
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Plavix For Acute Coronary Syndrome
Plavix is approved to reduce the risk of heart attack and stroke in people with acute coronary syndrome , which includes these three conditions:
- Unstable angina. This is a type of angina that may lead to a heart attack. The pain can occur when youre resting, or when youre physically active or stressed.
- Non-ST segment elevation myocardial infarction .NSTEMI is a type of heart attack that doesnt show ST-segment elevation on an electrocardiogram .
- ST-segment elevation myocardial infarction . This is a type of heart attack that does show ST-segment elevation on an EKG.
These conditions are typically caused by coronary artery disease . With CAD, theres a buildup of plaque in your arteries. Plaque formation causes your arteries to be partly or fully blocked, not allowing enough blood to flow through them. The lack of blood flow results in a lack of oxygen to your heart.
Symptoms of either unstable angina or heart attack can include:
- chest pain
- shortness of breath
Effectiveness in people with ACS
In clinical studies of people admitted to the hospital with ACS, people were given aspirin and either Plavix or a placebo . After up to 1 year of treatment, people using Plavix had fewer severe ACS complications than people who took the placebo. For details, see the Plavix package insert.
What Other Drugs Will Affect Vazalore
Ask your doctor before using Vazalore if you take an antidepressant. Taking certain antidepressants with this medicine may cause you to bruise or bleed easily.
Ask a doctor or pharmacist before using Vazalore with any other medications, especially:
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Plavix For Recent Heart Attack
Plavix is approved to reduce the risk of heart attack and stroke in people whove had a recent heart attack. Heart attacks occur when your heart doesnt get enough blood flow because of blocked blood vessels or other heart problems. This results in a lack of oxygen in your heart muscle and causes damage in your heart.
People whove had a heart attack in the past have a higher risk of having another one. Plavix has been shown to reduce this risk in people using the drug.
Effectiveness in people whove had a recent heart attack
A clinical study compared the use of Plavix versus aspirin in preventing heart attack, stroke, or cardiovascular-related death. The study looked at people whod had heart attack or stroke in the recent past, or people who had peripheral artery disease . After up to 3 years of treatment, fewer people taking Plavix had these serious effects. For details, see the Plavix package insert.
Before Taking This Medicine
Using Vazalore in a child or teenager with flu symptoms or chickenpox can cause a serious or fatal condition called Reye’s syndrome.
You should not use Vazalore if you are allergic to it, or if you have:
a recent history of stomach or intestinal bleeding
a bleeding disorder such as hemophilia or
if you have ever had an asthma attack or severe allergic reaction after taking Vazalore or an NSAID .
Tell your doctor if you have ever had:
Taking Vazalore during late pregnancy may cause bleeding in the mother or the baby during delivery. Tell your doctor if you are pregnant or plan to become pregnant.
You should not breastfeed while using Vazalore.
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