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Is Ibuprofen Bad For Your Liver Or Kidneys

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Does Meloxicam Have More Side Effects Than Ibuprofen

What Ibuprofen Does to the Body

Because meloxicam and ibuprofen are both NSAIDs, they have similar side effects, which may include abdominal pain, constipation, diarrhea, heartburn, nausea, tinnitus, and a rash.

All NSAIDs carry a risk of cardiovascular disease, including an increased risk for blood clots, stroke, or a heart attack however, the risk with meloxicam appears higher than with ibuprofen .

Meloxicam is also more likely than ibuprofen to cause gastrointestinal disturbances, such as gastric bleeding and ulceration. Consuming more than three alcoholic beverages per day while taking any NSAID increases the risk of GI disturbances.

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Is Tylenol Or Ibuprofen Worse For Your Kidneys

Unlike Ibuprofen and other NSAIDs, the active ingredient in Tylenol does not cause damage to the kidneys. In fact, the National KidneyFoundation recommends acetaminophen as the pain reliever of choice for occasional use in patients who have underlying kidney disease.

Although NSAIDs are more likely to cause kidney issues, Ibuprofen can still be used as long as it is not taken in excess. Unless otherwise directed by your physician, you should be just fine using Ibuprofen for occasional pain relief.

Newly Developed Fluid Retention

Ibuprofen sometimes causes newly developed fluid retention. This occurs primarily because the kidneys tend to retain extra salt and water under the influence of ibuprofen although noticeable fluid retention is uncommon and the risk differs among people. Young people in good health who occasionally take ibuprofen for minor pain or an illness rarely develop symptoms of fluid retention, such as eye or finger puffiness, swelling of feet and ankles, or weight gain. However, people with heart, liver or kidney disease and those with high blood pressure are more likely to develop fluid-retention symptoms.

  • Ibuprofen sometimes causes newly developed fluid retention.
  • Young people in good health who occasionally take ibuprofen for minor pain or an illness rarely develop symptoms of fluid retention, such as eye or finger puffiness, swelling of feet and ankles, or weight gain.

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My Friend Told Me To Take Liver Cleansing Agent

Examples of liver cleansing agents include, but are not limited to:

These supplements, and others like them, can cause harm to the liver. The best way to improve the liver is to identify the cause of the liver disease and treat it appropriately.

Herbal and dietary supplements are commonly used in the United States, often in combination or as multi-ingredient products. Many cases of liver injury caused by HDS have been documented in the literature, leaving little doubt as to the potential for harm. Drugs and HDSs were the second most common cause of acute liver failure, with acetaminophen being the most common.

How Should This Medicine Be Used

Kidney Damage From Ibuprofen

Prescription ibuprofen comes as a tablet to take by mouth. It is usually taken three or four times a day for arthritis or every 4 to 6 hours as needed for pain. Nonprescription ibuprofen comes as a tablet, chewable tablet, suspension , and drops . Adults and children older than 12 years of age may usually take nonprescription ibuprofen every 4 to 6 hours as needed for pain or fever. Children and infants may usually be given nonprescription ibuprofen every 6 to 8 hours as needed for pain or fever, but should not be given more than 4 doses in 24 hours. Ibuprofen may be taken with food or milk to prevent stomach upset. If you are taking ibuprofen on a regular basis, you should take it at the same time every day. Follow the directions on the package or prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Take ibuprofen exactly as directed. Do not take more or less of it or take it more often than directed by the package label or prescribed by your doctor.

Ibuprofen comes alone and in combination with other medications. Some of these combination products are available by prescription only, and some of these combination products are available without a prescription and are used to treat cough and cold symptoms and other conditions. If your doctor has prescribed a medication that contains ibuprofen, you should be careful not to take any nonprescription medications that also contain ibuprofen.

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And Take Advil Instead Of Tylenol If Youre Dealing With Any Pain Associated With Inflammation

If your pain is due to inflammation, then Advil is the better choice because it is a NSAID, Poston explains. Jessica Nouhavandi, PharmD, lead pharmacist and founder of online pharmacy Honeybee Health, says that Tylenol doesnt help with inflammation pain because it does not have that anti-inflammatory effect.

Advil blocks the production of chemicals in the body that contribute to pain and inflammationso whenever there is redness, swelling, heat, or pain at a site, says Oz. This makes it ideal for most back and neck pain, toothache, muscle sprains and strains, and menstrual cramps. And for more health advice, If You Drink This, You Could Become Resistant to Antibiotics, Study Says.

Whats The Difference Between Tylenol And Aspirin

âThe Healthy Geezerâ answers questions about health and aging in his weekly column.

Question: What is the difference between Tylenol and aspirin?

Answer: Acetaminophen is the most widely used pain-reliever and fever-reducer in the world. It is contained in more than 100 products.

Tylenol is the best known over-the-counter acetaminophen product. It is also a component of well-known prescription drugs such as Darvocet and Percocet. Acetaminophen also is known as paracetamol and N-acetyl-p-aminophenol .

There are basically two types of OTC pain relievers. Some contain acetaminophen, which is processed in the liver. Others contain non-steroidal anti-inflammatory drugs , which are processed elsewhere. Examples of OTC NSAIDs are aspirin, ibuprofen and naproxen sodium .

Taking too much acetaminophen can lead to liver damage. The risk for liver damage may be increased if you drink three or more alcoholic drinks while using medicines that contain acetaminophen.

Acetaminophen is one of the most common pharmaceutical agents involved in overdose, as reported to the American Association of Poison Control Centers.

NSAIDs are associated with stomach distress. You should talk to your doctor before using NSAIDS if you are over 60, taking prescription blood thinners, or have stomach ulcers or other bleeding problems.

Itâs a good idea for all older adults to consult their doctors before taking any OTC medication.

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Dosage Of Ibuprofen Or Acetaminophen

For the treatment of mild to moderate pain, minor fever, and acute or chronic inflammatory conditions 200 mg to 400 mg of ibuprofen will work, and is similar to 650 mg of acetaminophen or aspirin. Typically taken every 6 to 8 hours, the optimum dose of NSAIDs per day is 2400 mg which is 12 over-the-counter pills.

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Take Milk Thistle It Is Good For The Liver

Combining ibuprofen and blood pressure medications might be bad for your kidneys

Silymarin is a mixture of flavonolignans extracted from the milk thistle and has a history as a medical plant for almost two millennia. The main component of silymarin is silibinin. Silibinin has strong antioxidative and antifibrotic properties, which make it a potentially useful drug for treatment of chronic liver diseases. However, extensive first-pass metabolism in the intestine and the liver are responsible for low oral bioavailabilities of flavonoids, meaning the levels in the blood are low.

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How Does Ibuprofen Or Acetaminophen Affect To Kidney

NSAIDs have important unfavorable effects on the kidney that you should know about.

Here is the science behind the issue. Ibuprofen and other NSAIDs hinder prostaglandins, and that can cause an issue due to the fact that prostaglandins dilate capillary resulting in the kidneys, according to Preventing prostaglandins may result in kidney anemia and therefore severe kidney injury.

A simple blood test might show a rise in creatinine if your kidneys are being affected, typically seen within the first 3 to seven days of NSAID therapy. Severe kidney injury can occur with any NSAID though naproxen appears to be a bigger culprit. In one study, folks who took NSAIDs had twice the risk of acute kidney injury within 30 days of starting to take the NSAIDs. Good news is its reversible if you stop taking them.

In individuals with hypertension, taking NSAIDs long term may aggravate underlying hypertension. Individuals with kidney problems at baseline regularly get in difficulty with NSAIDs, however if you are taking ibuprofen for extended periods of time its not a bad idea to have a check of your kidney function with a quick blood test. Keep in mind, intense kidney injury from NSAIDs does not cause any symptoms.


NSAIDs are safe for the liver, but can cause a problem with kidney function that is reversible if you stop taking them. Typically safe but worth taking notice of.

Kidney Health Problems Linked To Ibuprofen Use

The widely used, non-prescription pain reliever ibuprofen is increasingly being linked to serious long-term health problems, including kidney failure, according to two new studies.

One report, a small study of 12 patients at the Johns Hopkins Medical Institutions in Baltimore, found that one-quarter of those who took the drug developed acute kidney failure, that was reversed once the drug was stopped. The study will be published later this year in the Annals of Internal Medicine.

A second study of 554 adults by researchers at the National Institute for Environmental Health Sciences found that ibuprofen can cause kidney failure in individuals with other health problems, such as high blood pressure, heart disease and pre-existing kidney problems. That report, which is the second part of a study published last spring in the New England Journal of Medicine, was presented in July at the Fourth International Nephrotoxicity Symposium in England.

Our concern is that if patients take this stuff for great lengths of time and not just in short bursts of therapy that they could wind up with kidney damage, said William L. Henrich, a kidney specialist and professor of medicine at the University of Texas Southwestern Medical School in Dallas.

Higher doses of ibuprofen are available by prescription, and in September, the Food and Drug Administration approved the use of a liquid form of the drug, available only by prescription, for children under 12.

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How Is Ibuprofen Poisoning Diagnosed

Most cases are diagnosed in pets that have the expected signs and a known or suspected exposure to ibuprofen. Bloodwork to evaluate organ function and blood cell counts are commonly performed A urinalysis may also be recommended.

Ibuprofen levels in the blood can be measured at a human hospital or specialized laboratory, although, testing for ibuprofen levels is uncommon in veterinary medicine.

Painkillers And The Kidneys: Analgesic Nephropathy

Kidney Damage Tylenol

An analgesic is any medicine intended to relieve pain. Over-the-counter analgesics include aspirin, acetaminophen, ibuprofen, naproxen sodium, and others. These drugs present no danger for most people when taken in the recommended dosage. But some conditions make taking even these common painkillers dangerous for the kidneys. Also, taking one or a combination of these drugs regularly over a long period of time may increase the risk for kidney problems. Most drugs that can cause kidney damage are excreted only through the kidneys.

Analgesic use has been associated with two different forms of kidney damage. Some patient case reports have attributed incidents of sudden-onset acute kidney failure to the use of over-the-counter painkillers, including aspirin, ibuprofen, and naproxen. The patients in these reports had risk factors such as systemic lupus erythematosus, advanced age, chronic kidney disease, or recent heavy alcohol consumption. These cases involved a single dose in some instances and generally short-term analgesic use of not more than 10 days. Acute kidney failure requires emergency dialysis to clean the blood. Kidney damage is frequently reversible, with normal kidney function returning after the emergency is over and the analgesic use is stopped.

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Why Is Advil Bad For Your Kidneys If It Is Processed By The Liver And Tylenol Not So Harmful When I

10 Jan 2014 by Twfinklea


Advil, Excedrin, and Motrin have Ibuprofen in them. Aspirin and Ibuprofen are not good for people with kidney disease. I have Chronic Kidney Disease Stage 3, and aspirin caused me to go into Acute Renal Failure. My Nephrologist told me, NO aspirin, NO ibuprofen. Advil and Excedrin were the only thing that helped me with headaches or arthritis pain and it has been very hard for me to stick to Tylenol. You can be sure if you take too much Tylenol, it can also cause issues with the kidneys, so I take 1/2 the dose of 500 mg. Drinking lots of water has helped more than anything. Most people dont take medication with a full glass of water. Just a sip will do they think. But to protect your body parts, use lots of water.Hope this helps.

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When Acetaminophen Does Injure The Liver

More good news: Its unlikely that taking acetaminophen over time causes chronic liver disease or cirrhosis. And when acetaminophen does cause liver injury, there is an effective antidote that can reverse the damage when started early. This drug is called N-acetylcysteine, or NAC. Most patients who receive NAC within 24 to 48 hours of an overdose of acetaminophen get better, and even those who progress to liver failure usually recover without the need for a liver transplant. Because of this, liver injury from acetaminophen is considered an all-or-none phenomenon that is, either the patient doesnt recover and needs a liver transplant to survive, or there is complete recovery without long-term liver damage.

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Your Stomach Will Start To Hurt If You Take Ibuprofen Every Day

If you take ibuprofen every day, you just might find yourself doubled over with a tummy-ache.

One of the most common side effects that come from taking ibuprofen every day is stomach pain. And if youâre taking the pills daily on an empty stomach, you better believe your body wonât be thanking you for that. As noted by Everyday Health, as many as 50 percent of people who have tried ibuprofen for their aches and pains are unable to rely on the medication due to the abdominal pain, diarrhea, and other tummy troubles it causes them. So, if youâve been popping ibuprofen like candy for a while, you might want to rethink that decision moving forward.

According to the Advil website, the NSAID can also cause âsevere stomach bleeding,â which would call for a trip to the emergency room. Of course, if youâve noticed slight discomfort after taking ibuprofen without food, it might help to eat a little something with the medication. However, if ibuprofen causes stomach pain even when taken with food, you should probably talk to your doctor about alternative medications, or scientifically proven natural remedies.

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What Are The Clinical Signs Of Ibuprofen Poisoning

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Ibuprofen poisoning may cause many different signs because several organ systems can be affected. Signs can vary depending upon the dose and product to which the dog was exposed.

Most commonly , signs related to irritation and ulceration of the gastrointestinal tract are seen. These may include decreased appetite, vomiting , diarrhea, depression, abdominal pain, dark tarry stools, pale gums, and bloody stools.

Other signs can include incoordination, increased or decreased drinking and urination, yellow discoloration of the skin and mucous membranes pale mucous membranes, agitation, tremors, seizures, and coma.

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Fatality Due To Ibuprofen

Compared with acetaminophen, ibuprofen is more potent, affects the elderly more, and occurs for a longer onset time on average, but the mortality rate is only one-sixth of that of ibuprofen . Maybe this anomaly is also related to their mechanisms. Acetaminophen-associated kidney injury is often accompanied by liver damage and AKI correlates with more severe liver injury in patients . In our research, liver injury as the most reported complication of kidney injury, far exceeds the second-ranked symptom of poisoning. Thus, the dysfunction of two important organs may occur simultaneously in a short period of time, which may overwhelm patients and eventually lead to death. However, ibuprofen-related kidney injury is more likely to occur over a long period of time, giving pharmacists and physicians more time to correct the renal dysfunction. In addition, in our study, the number of suicides using acetaminophen was significantly higher than that of ibuprofen . Based on this, the death rate of APAP-related kidney injury may increase due to the presence of more suicides. However, after excluding the suicide population, the mortality rate of APAP-related kidney injury is still significantly higher than that of ibuprofen, which means that the impact of suicide may not be as large as we thought.

What Color Is Urine When Your Kidneys Are Failing

When kidneys are failing, the increased concentration and accumulation of substances in urine lead to a darker color which may be brown, red or purple. The color change is due to abnormal protein or sugar, high levels of red and white blood cells, and high numbers of tube-shaped particles called cellular casts.

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Who Can Take Ibuprofen

Some people should avoid using ibuprofen and others should use it with caution. If you have any queries about using ibuprofen or any other medicines, speak to your GP or pharmacist, or phone the NHS 24 111 service.

You shouldnât take ibuprofen if you:

  • have a history of a strong, unpleasant reaction to aspirin or other NSAIDs
  • have a current or recent stomach ulcer, or you have had one in the past

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